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CJC-1295 / Ipamorelin Blend: Reconstitution & Units

Last updated: July 2026

To reconstitute a combined CJC-1295 and ipamorelin blend vial, add your chosen volume of bacteriostatic water, then work out the concentration of each peptide separately — a “10 mg blend” is usually 5 mg of each, not 10 mg of one. Because the two peptides are pre-mixed in a fixed ratio inside a single vial, one draw always delivers both at once, and the number of syringe units you pull depends entirely on how much water you added.

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TL;DR — key takeaways

  • “Total mg” is a trap. A blend advertised as 10 mg is typically 5 mg CJC-1295 + 5 mg ipamorelin. Read the label for the per-peptide amounts.
  • One ratio, one draw. The two peptides are mixed before lyophilisation, so you cannot dose them independently — drawing enough for 100 mcg of CJC-1295 also delivers 100 mcg of ipamorelin in a 1:1 blend.
  • Water sets the units, not the dose. The milligrams in the vial are fixed; adding more bacteriostatic water simply spreads them over more volume, so each unit carries fewer micrograms.
  • Investigational. Neither CJC-1295 nor ipamorelin is FDA-approved for human use. This page is reconstitution arithmetic, not a protocol or medical advice.

What is in a CJC-1295 / ipamorelin blend vial

CJC-1295 is a growth-hormone-releasing hormone (GHRH) analogue; the version sold for research is almost always the “no-DAC” form, also written CJC-1295 DAC-free or mod-GRF(1-29). Ipamorelin is a selective growth hormone secretagogue that acts on a different receptor (the ghrelin/GHS receptor). The two are frequently combined because they stimulate growth-hormone release through complementary pathways, and vendors lyophilise them together as a single powder so one injection covers both.

That convenience is also the catch: once the powder is mixed, the ratio between the two peptides is locked. If the vial holds 5 mg of each, every microlitre you draw contains equal parts CJC-1295 and ipamorelin. You reconstitute the whole vial once and treat the pair as your unit of dosing.

Reading the label: per-peptide, not total

Blend labels are written several ways — “CJC-1295 5 mg / Ipamorelin 5 mg”, “5​/​5 blend”, or the ambiguous “10 mg blend.” The safe assumption is that a two-number label lists each peptide, and a single “total” number is the sum of both. When in doubt, use the smaller per-peptide figure for your maths, because under-filling the syringe is far easier to correct than an accidental double dose.

Worked example 1 — the “total mg” trap

A vial is sold as a 10 mg blend. It actually contains 5 mg CJC-1295 and 5 mg ipamorelin. Treating it as 10 mg of CJC-1295 would double your intended peptide amount. Always split the total across the two named peptides first.

Step 1 — find each peptide's concentration

Concentration is amount ÷ volume. Do it once per peptide. For a 1:1 blend the two concentrations are identical, which is why people often just track “mcg per unit” for the pair.

Worked example 2 — 5/5 blend + 2 mL

Add 2 mL bacteriostatic water to a 5 mg​/​5 mg vial.

CJC-1295: 5 mg ÷ 2 mL = 2.5 mg/mL. Ipamorelin: 5 mg ÷ 2 mL = 2.5 mg/mL.

On a U-100 syringe (100 units = 1 mL), each unit holds 25 mcg CJC-1295 + 25 mcg ipamorelin.

Step 2 — convert your dose to units

Once you know micrograms-per-unit, divide your target dose by it. On a U-100 syringe, units = (dose in mL) × 100, and dose in mL = dose in mcg ÷ concentration in mcg/mL.

Worked example 3 — 100 mcg each from the 2 mL fill

Using the 2.5 mg/mL (2500 mcg/mL) concentration above, a 100 mcg dose of each peptide:

100 mcg ÷ 2500 mcg/mL = 0.04 mL.  0.04 mL × 100 = 4 units.

Draw 4 units → delivers 100 mcg CJC-1295 + 100 mcg ipamorelin.

Worked example 4 — same vial, 1 mL of water

Reconstitute the same 5​/​5 vial with only 1 mL: each peptide is now 5 mg/mL (5000 mcg/mL), so each unit carries 50 mcg of each.

A 100 mcg dose = 100 ÷ 5000 = 0.02 mL = 2 units — half the volume of Example 3 for the identical dose.

Worked example 5 — same vial, 3 mL of water

With 3 mL, each peptide is 1.667 mg/mL (1667 mcg/mL).

100 mcg ÷ 1667 mcg/mL = 0.06 mL = 6 units. More water, more units, same dose.

How bacteriostatic water changes the draw

The three examples above use one vial and one dose, yet the syringe reads 2, 4, or 6 units depending only on the water. This is the single most common source of confusion with any reconstituted peptide: the units on the barrel measure volume, and volume is something you choose when you reconstitute. The diagram shows the same 100 mcg dose drawn from the same 5​/​5 vial at three fill volumes.

Same 100 mcg dose, U-100 syringe 1 mL 2 u 2 mL 4 u 3 mL 6 u More bacteriostatic water → the same dose spreads across more units

Dose-to-units reference chart

Units per dose for a 5 mg​/​5 mg blend at three common fill volumes. Each figure delivers that dose of both peptides at once. Confirm against your own vial label.

Dose (each peptide)+1 mL (50 mcg/u)+2 mL (25 mcg/u)+3 mL (16.7 mcg/u)
100 mcg2 units4 units6 units
150 mcg3 units6 units9 units
200 mcg4 units8 units12 units
300 mcg6 units12 units18 units

Worked example 6 — a smaller 2/2 blend

A 2 mg CJC-1295 + 2 mg ipamorelin vial reconstituted with 2 mL: each peptide is 1 mg/mL (1000 mcg/mL), so each unit carries 10 mcg of each.

A 100 mcg dose = 100 ÷ 1000 = 0.1 mL = 10 units.

Worked example 7 — a larger 10/10 blend

A 10 mg + 10 mg vial with 2 mL: each peptide is 5 mg/mL (5000 mcg/mL), 50 mcg per unit.

A 100 mcg dose = 2 units; a 300 mcg dose = 6 units. Same arithmetic, different vial strength.

Worked example 8 — how long a vial lasts

A 5​/​5 blend dosed at 100 mcg of each peptide per injection: 5000 mcg ÷ 100 mcg = 50 doses of each. Because the ratio is 1:1, both peptides run out on the same injection — a deliberate advantage of a matched blend.

How this is calculated

Every number here comes from two facts: a U-100 syringe holds 100 units per millilitre, and concentration is amount ÷ volume. The only twist for a blend is doing the concentration step once per peptide, then dosing the fixed pair together. There is no drug-specific constant and no clinical judgement baked in — it is the same arithmetic our peptide reconstitution calculator runs, shown so you can check it by hand. This is an educational maths tool, not medical advice.

Safety and honesty notes

CJC-1295 and ipamorelin are research peptides. Neither is approved by the FDA for human use, and both were flagged in the FDA's review of bulk drug substances for compounding. Human data are limited: the pivotal CJC-1295 studies were small pharmacokinetic trials in healthy adults, and the foundational ipamorelin work was preclinical. Independent reviews of growth-hormone secretagogues note that long-term, rigorously controlled safety data are scarce. Nothing on this page endorses use — it exists so that anyone handed a blend vial can read the label correctly and avoid a dosing error.

Frequently asked questions

Does a “10 mg blend” mean 10 mg of CJC-1295?

Usually no. A two-peptide blend labelled 10 mg is typically 5 mg of each. Treat a single total as the sum and split it across both named peptides before doing any maths.

Can I dose CJC-1295 and ipamorelin separately from a blend vial?

No. Once they are lyophilised together the ratio is fixed, so one draw delivers both in that ratio. To dose them independently you would need two separate vials.

Why do the same milligrams give different unit counts?

Units measure volume, and volume depends on how much bacteriostatic water you added. More water spreads the same peptide over more units, so each unit carries fewer micrograms.

Does more bacteriostatic water make the dose weaker?

No. The milligrams in the vial do not change. More water only changes how many units correspond to your dose — you simply draw a larger volume for the same amount of peptide.

Sources

  1. Teichman SL, et al. Prolonged stimulation of GH and IGF-I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults (J Clin Endocrinol Metab 2006)
  2. Ionescu M, Frohman LA. Pulsatile secretion of GH persists during continuous stimulation by CJC-1295, a long-acting GHRH analog (J Clin Endocrinol Metab 2006)
  3. Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue (Eur J Endocrinol 1998)
  4. Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues (Sex Med Rev 2018)
  5. Bacteriostatic Water for Injection, USP (benzyl alcohol, multiple-dose) — DailyMed / FDA label

This guide is for general educational purposes only and does not constitute medical advice. Always follow your prescriber’s specific instructions and consult a qualified clinician before changing any protocol.