Last updated: June 2026

NPP Dosage Calculator

Quick answer: A 100 mg/week dose over 3.5 shots from a 100 mg/mL vial is 0.286 mL (28.6 units) per shot, ≈ 67 mg active hormone/week. mL = (weekly mg ÷ shots) ÷ mg/mL.

Key takeaways

Injectable ester — about 67% of each mg is NPP; the calculator converts dose → mL, units and active mg. Aromatizes: Partial / weak. Liver-strain (17α-alkylated): No. Half-life: ≈ 2.7 days (65 h) oil-depot; free nandrolone clears in < 4.3 h.

About this calculator

NPP is the short-ester form of nandrolone (19-nortestosterone). About 67% of each milligram is active nandrolone. This calculator converts your weekly dose into draw volume and syringe units, and shows the depot half-life that drives its more-frequent injection schedule versus long-ester Deca.

NPP is nandrolone attached to the short phenylpropionate ester — the fast counterpart to long-ester Deca-Durabolin. It is usually supplied at 100 mg/mL, and about 67% of each milligram is the parent hormone.

How the injection-volume maths works

The phenylpropionate ester accounts for a third of the molecule’s weight (274.4 ÷ 406.6 = 0.67), so a 100 mg dose delivers about 67 mg of nandrolone. The calculator shows that active figure alongside the draw volume.

How to use this calculator

Enter your weekly dose, the concentration printed on your vial (mg/mL), and how many injections per week. The result updates instantly with the mL to draw, the U-100 syringe units, and the active-hormone milligrams delivered.

Worked examples

Example 1

Weekly dose: 100 mg · Concentration: 100 mg/mL · Injections/week: 3.5

28.57 mg/shot ÷ 100 = 0.286 mL (28.6 units) · active ≈ 67 mg/week

Example 2

Weekly dose: 150 mg · Concentration: 100 mg/mL · Injections/week: 3

50 mg/shot ÷ 100 = 0.5 mL (50 units) · active ≈ 101 mg/week

NPP dose chart

Common doses at 100 mg/mL, 2 injections/week (each row is the calculator’s arithmetic worked out):

Weekly dosemL/shotUnitsActive/week
50 mg0.25 mL2534 mg
75 mg0.375 mL37.550 mg
100 mg0.5 mL5067 mg
150 mg0.75 mL75101 mg
200 mg1 mL100134 mg

Half-life & clearance

% remaining 3d5d8d11d14d100%50%25%13%6%3%

Illustrative single-dose elimination by half-life (t½ ≈ 3 days). Each marker is one half-life; after ~5 the dose is essentially cleared. For an oil depot the real rise-and-fall is slower (absorption-limited release), so treat this as a timing reference, not a blood-level prediction.

NPP 67% ester 33% Per 100 mg dosed → 67 mg parent hormone

With a ~2–3 day depot, NPP is injected more often than Deca to keep levels steady; once the ester is cleaved, free nandrolone itself clears within hours (Minto 1997). The 19-norandrosterone metabolite, however, remains detectable for months.

How to interpret your result

The result is the volume to draw per injection and its mark on a U-100 syringe. The active-hormone figure shows how much actual NPP that ester delivers — useful when comparing esters or switching concentrations. The half-life figure is a pharmacokinetic timing reference only.

Aromatization, liver & monitoring

Nandrolone aromatizes only weakly but is strongly progestogenic, which drives its own estrogen-like and prolactin-related effects. It is not 17α-alkylated, so it is not directly hepatotoxic.

Common mistakes

Treating NPP and Deca as interchangeable is the common error — they share the parent hormone but their esters give very different injection frequencies and active fractions (0.67 vs 0.64).

NPP at a glance

PropertyNPP
FormInjectable (oil/suspension)
Active fraction0.67 (esterFactor)
Half-life≈ 2.7 days (65 h) oil-depot; free nandrolone clears in < 4.3 h
AromatizesPartial / weak — aromatizes far less than testosterone; mainly progestogenic.
Liver (17α-alkylated)No (not 17α-alkylated).
Approx. detectionVery long — the 19-norandrosterone marker is detectable for months.

Frequently asked questions

How do I calculate my NPP dose?
Divide your weekly dose by the number of injections, then by the vial concentration: mL = (weekly mg ÷ shots) ÷ mg/mL, then × 100 for U-100 units. For example, 100 mg/week over 3.5 shots at 100 mg/mL is 0.286 mL (28.6 units) per shot.
What is the active-hormone amount for NPP?
NPP is an ester, so only part of each milligram is hormone. Its esterFactor is 0.67 (parent MW 274.4 ÷ ester MW 406.6), so a 100 mg dose delivers about 67 mg of the parent hormone.
What is the half-life of NPP?
≈ 2.7 days (65 h) oil-depot; free nandrolone clears in < 4.3 h.
Does NPP aromatize or stress the liver?
Aromatizes: Partial / weak — aromatizes far less than testosterone; mainly progestogenic. 17α-alkylated (liver strain): No (not 17α-alkylated).
Is this medical advice?
No. This is an educational arithmetic tool. It converts the numbers you enter, stores nothing, and does not recommend any dose, cycle, or protocol. Anabolic steroid use carries real health risks — consult a qualified clinician.

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References

  1. Minto CF et al. Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle. J Pharmacol Exp Ther 1997;281(1):93–102 (PMID 9316843)
  2. PubChem — nandrolone (molecular weight), CID 9904
  3. PubChem — nandrolone phenylpropionate (molecular weight), CID 229455
  4. Kicman AT. Pharmacology of anabolic steroids. Br J Pharmacol 2008;154(3):502–521

Every citation URL was verified to return HTTP 200. Citations are provided for transparency and education and do not imply the cited authors or bodies endorse this tool. Anabolic steroid use carries real health risks — always consult a qualified clinician.

How this is calculated

For injectables the calculator divides your weekly dose by the number of injections, then by the vial concentration, to get the mL per shot — and multiplies by 100 for U-100 syringe units (1 mL = 100 units). The active-hormone milligrams are the dose multiplied by the esterFactor (the parent hormone’s molecular weight divided by the full ester’s molecular weight, both from PubChem). For orals it divides the daily dose by your doses-per-day and tablet strength to get tablets per dose. Half-life timing uses ke = ln2 ÷ t½ and the ~5-half-life rule of thumb for steady state and clearance. It is arithmetic only — nothing you enter is stored or sent anywhere, and the result is not medical advice or an endorsement of anabolic steroid use.

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